Exhibit 99.46 MBNA MASTER CREDIT CARD TRUST II SERIES 2000-E KEY PERFORMANCE FACTORS November 30, 2000 Expected B Maturity 05/17/2010 Blended Coupon 7.9030% Excess Protection Level 3 Month Average 5.93% November, 2000 6.22% October, 2000 6.05% September, 2000 5.51% Cash Yield19.74% Investor Charge Offs 4.46% Base Rate 9.06% Over 30 Day Delinquency 5.24% Seller's Interest11.84% Total Payment Rate13.77% Total Principal Balance$56,372,819,075.31 Investor Participation Amount$590,000,000.00 Seller Participation Amount$6,672,128,513.82