Exhibit 99.46 MBNA MASTER CREDIT CARD TRUST II SERIES 2000-E KEY PERFORMANCE FACTORS December 31, 2000 Expected B Maturity 05/17/2010 Blended Coupon 7.9030% Excess Protection Level 3 Month Average 4.13% December, 2000 0.12% November, 2000 6.22% October, 2000 6.05% Cash Yield19.79% Investor Charge Offs10.15% Base Rate 9.53% Over 30 Day Delinquency 4.72% Seller's Interest10.47% Total Payment Rate13.35% Total Principal Balance$57,190,978,436.47 Investor Participation Amount$590,000,000.00 Seller Participation Amount$5,990,287,874.98